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SCIENTIFIC SCORE
Moderately Effective
Based on 48 Researches
8
USERS' SCORE
Good
Based on 47 Reviews
8.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
9.5
Lactococcus lactis shows promise for T1DM
Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice.
High relevance for autoimmune research
We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
Read More
9
LC-STH-13 counters lupus effects
LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway.
High relevance, promising findings
We explored the effects of probiotic LC-STH-13 on systemic lupus erythematosus (SLE) in MRL/lpr mice. Our study demonstrated that LC-STH-13 significantly decreased harmful autoantibodies and rebalanced specific immune cells.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
Read More
9
Lactobacillus rhamnosus mitigates gliadin's effects
The protective role of GG postbiotic on the alteration of autophagy and inflammation pathways induced by gliadin in intestinal models.
Study shows viable celiac treatment potential.
We investigated the effects of Lactobacillus rhamnosus GG (LGG) in combating inflammation and cellular changes caused by gliadin in celiac disease models. Our study found that pretreating intestinal cells with LGG postbiotics stopped the activation of harmful pathways linked to gliadin, such as mTOR and NF-κβ. Notably, this protective effect was also observed in more complex models using organoids derived from celiac patients. While these findings are promising, further research is necessary to fully understand LGG’s potential benefits in managing celiac disease.
Read More
Most Useful Reviews
9.5
Pain relief achieved
Since taking one NATOOSHCHAK capsule each morning, my chronic colitis pain and swelling have decreased significantly. These enteric capsules are a major plus, and I ensure to keep them refrigerated for longevity. I've noticed great health benefits.
Read More
9.5
Improved digestion
These probiotics significantly improved my digestive health. I had struggled with diets and irregularity, but since starting them, my body functions much better, and my skin is clearer. I recommend these; they have effectively solved my issues!
Read More
9.5
Nausea alleviated
I took these probiotics to deal with occasional nausea and digestive rejection. They worked wonders in just half an hour, easing all negative symptoms. I'm quite impressed and plan to order them again.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 48 Researches
8
9.5
Lactococcus lactis shows promise for T1DM
Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice.
High relevance for autoimmune research
We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
Read More
9
Probiotics may aid rheumatoid arthritis
The Impacts of and to Promote In Vitro Anti-Inflammatory Profile of RA-Macrophages.
High relevance to autoimmune treatment
We examined how probiotics, specifically Lactobacillus rhamnosus, could help with rheumatoid arthritis (RA) symptoms. By isolating monocytes from RA patients and healthy individuals, we created macrophages and tested various treatments.
Our findings revealed that probiotics encouraged macrophages to adopt a more anti-inflammatory state. They increased beneficial cytokines while lowering inflammatory ones. This suggests a potential role for probiotics in managing RA, showing they might help modulate immune responses and improve symptoms.
Our findings revealed that probiotics encouraged macrophages to adopt a more anti-inflammatory state. They increased beneficial cytokines while lowering inflammatory ones. This suggests a potential role for probiotics in managing RA, showing they might help modulate immune responses and improve symptoms.
Read More
9
LC-STH-13 counters lupus effects
LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway.
High relevance, promising findings
We explored the effects of probiotic LC-STH-13 on systemic lupus erythematosus (SLE) in MRL/lpr mice. Our study demonstrated that LC-STH-13 significantly decreased harmful autoantibodies and rebalanced specific immune cells.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
Read More
9
Lactobacillus rhamnosus mitigates gliadin's effects
The protective role of GG postbiotic on the alteration of autophagy and inflammation pathways induced by gliadin in intestinal models.
Study shows viable celiac treatment potential.
We investigated the effects of Lactobacillus rhamnosus GG (LGG) in combating inflammation and cellular changes caused by gliadin in celiac disease models. Our study found that pretreating intestinal cells with LGG postbiotics stopped the activation of harmful pathways linked to gliadin, such as mTOR and NF-κβ. Notably, this protective effect was also observed in more complex models using organoids derived from celiac patients. While these findings are promising, further research is necessary to fully understand LGG’s potential benefits in managing celiac disease.
Read More
9
Probiotics may aid IBD recovery
The Gut-Ex-Vivo System (GEVS) Is a Dynamic and Versatile Tool for the Study of DNBS-Induced IBD in BALB/C and C57BL/6 Mice, Highlighting the Protective Role of Probiotics.
Study shows strong probiotic effects.
We explored the effectiveness of probiotics in treating inflammatory bowel disease (IBD) using a novel Gut-Ex-Vivo System (GEVS). Through careful examination, we found that probiotics notably counteracted the negative effects of colon inflammation caused by DNBS in mice.
Our results revealed that probiotics could significantly help restore gut health by promoting the remission of IBD symptoms. This innovative method presents a promising avenue for future research into IBD therapies while also being kind to animal subjects.
Our results revealed that probiotics could significantly help restore gut health by promoting the remission of IBD symptoms. This innovative method presents a promising avenue for future research into IBD therapies while also being kind to animal subjects.
Read More
User Reviews
USERS' SCORE
Good
Based on 47 Reviews
8.6
10
Balanced digestion restored
Despite being sceptical about these probiotics affecting my IBS, they worked wonders! I felt relief from unpleasant symptoms within 30 minutes. They’re now part of my regular routine, and I’m grateful for the sample that introduced me to them.
9.5
Pain relief achieved
Since taking one NATOOSHCHAK capsule each morning, my chronic colitis pain and swelling have decreased significantly. These enteric capsules are a major plus, and I ensure to keep them refrigerated for longevity. I've noticed great health benefits.
9.5
Improved digestion
These probiotics significantly improved my digestive health. I had struggled with diets and irregularity, but since starting them, my body functions much better, and my skin is clearer. I recommend these; they have effectively solved my issues!
9.5
Nausea alleviated
I took these probiotics to deal with occasional nausea and digestive rejection. They worked wonders in just half an hour, easing all negative symptoms. I'm quite impressed and plan to order them again.
9.5
Diarrhoea stopped
After suffering from a lifetime of diarrhoea linked to my autoimmune disorder, these probiotics were transformative. Doubling the recommended dose resulted in perfectly normal poops and resolved my issues, even helping a friend with constipation. I plan to reorder soon.
